DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0007342)

Number of enzymes:	2
Number of disease:	1
Number of reactomes:	3
Number of reactions:	6

Search results (Disease ID: MONDO:0007342)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007342	KAT6B	Q8WYB5	2.3.1.48	R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome	R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome	Chromatin organization	R-HSA-3318486 ( R-HSA-3214847 ) R-HSA-3318486 Reaction Name: KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 See in Reactome
MONDO:0007342	INPP5E	Q9NRR6	3.1.3.36 3.1.3.86	R-HSA-1660514 R-HSA-1660514 Reactome Name: Synthesis of PIPs at the Golgi membrane See in Reactome R-HSA-5624958 R-HSA-5624958 Reactome Name: ARL13B-mediated ciliary trafficking of INPP5E See in Reactome	R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-1483255 R-HSA-1483255 Reactome Name: PI Metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5620920 R-HSA-5620920 Reactome Name: Cargo trafficking to the periciliary membrane See in Reactome R-HSA-5617833 R-HSA-5617833 Reactome Name: Cilium Assembly See in Reactome	Organelle biogenesis and maintenance Metabolism	R-HSA-1675824 ( R-HSA-1660514 ) R-HSA-1675824 Reaction Name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane See in Reactome R-HSA-5624953 ( R-HSA-5624958 ) R-HSA-5624953 Reaction Name: ARL13B binds INPP5E See in Reactome R-HSA-5624954 ( R-HSA-5624958 ) R-HSA-5624954 Reaction Name: INPP5E translocates to the primary cilium See in Reactome R-HSA-5624956 ( R-HSA-5624958 ) R-HSA-5624956 Reaction Name: PDE6D binds INPP5E See in Reactome R-HSA-5638012 ( R-HSA-5624958 ) R-HSA-5638012 Reaction Name: PDE6D dissociates from ARL13B:INPP5E See in Reactome